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MED12

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抑制剂 & 激动剂

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重组蛋白

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  • HY-P701363
    CDK19-CCNC-MED12 Protein, Human (Sf9)

    CDK19; CCNC; MED12; Cyclin-dependent kinase 19; CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinase; Cyclin-C; SRB11 homolog; hSRB11; MEDiator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; MEDiator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein

    		 Human Sf9 insect cells
    CDK19 在细胞稳态和发育编程中发挥着关键作用。CDK19 可与 p53 相互作用，抑制 p53 介导的 p21 转录，调节造血干细胞和急性髓性白血病细胞的增殖。此外，CDK19 是 CDK8 的旁系同源物。CDK8 和 CDK19 可以相互配合支持白血病细胞生长、刺激 NFκB 诱导的转录和登革热病毒复制。CDK19-CCNC-MED12 Protein, Human (Sf9) 是重组的 CDK19-CCNC-MED12 蛋白，由 Sf9 insect cells 表达，不带标签。CDK19-CCNC-MED12 Protein, Human (Sf9) 。
  • HY-P701373
    CDK8-CCNC-MED12 Protein, Human (Sf9, GST, FLAG, His)

    CDK8; CCNC; MED12; Cyclin-dependent kinase 8; Cell division protein kinase 8; MEDiator complex subunit CDK8; MEDiator of RNA polymerase II transcription subunit CDK8; Protein kinase K35; Cyclin-C; SRB11 homolog; hSRB11; MEDiator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; MEDiator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein

    		 Human Sf9 insect cells
    CDK8-CCNC-MED12蛋白是介导复合物的重要组成部分，充当基因转录调控的桥梁，将信息从基因特异性调控因子传递到RNA聚合酶II。它被招募到启动子，组装预起始复合物并促进转录。CDK8-CCNC-MED12 Protein, Human (Sf9, GST, FLAG, His) 是重组的 CDK8-CCNC-MED12 蛋白，由 Sf9 insect cells 表达，带有 N-6*His, N-Flag, N-GST 标签。
  • HY-P701372
    CDK8-CCNC-MED12 Protein, Human (Sf9)

    CDK8; CCNC; MED12; Cyclin-dependent kinase 8; Cell division protein kinase 8; MEDiator complex subunit CDK8; MEDiator of RNA polymerase II transcription subunit CDK8; Protein kinase K35; Cyclin-C; SRB11 homolog; hSRB11; MEDiator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; MEDiator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein

    		 Human Sf9 insect cells
    CDK8-CCNC-MED12蛋白是介导复合物的重要组成部分，充当基因转录调控的桥梁，将信息从基因特异性调控因子传递到RNA聚合酶II。它被招募到启动子，组装预起始复合物并促进转录。CDK8-CCNC-MED12 Protein, Human (Sf9) 是重组的 CDK8-CCNC-MED12 蛋白，由 Sf9 insect cells 表达，不带标签。
  • HY-P702699
    CDK19-CCNC-MED12 Protein, Human (sf9, GST, Flag, His)

    CDC2L6; CDK19; cyclin dependent kinase 19; CDK11; CDC2L6; bA346C16.3; cyclin-dependent kinase 19; CDC2-related protein kinase 6; CDK8-like cyclin-dependent kinase; cell division cycle 2-like 6 (CDK8-like); cell division cycle 2-like protein kinase 6; cell division protein kinase 19; cyclin dependent kinase 19 variant 2; cyclin-dependent kinase (CDC2-like) 11; cyclin-dependent kinase 11; death-preventing kinase; EC 2.7.11.22

    		 Human Sf9 insect cells

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