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  3. SKF-34288 hydrochloride

SKF-34288 hydrochloride (Synonyms: 3-Mercaptopicolinic acid hydrochloride)

目录号: HY-128923
产品使用指南

SKF-34288 hydrochloride 是磷酸烯醇丙酮酸羧激酶 (PEPCK) 抑制剂。SKF-34288 hydrochloride 通过糖异生途径中 PEPCK 的特异性抑制来抑制葡萄糖合成,是一种有效的降血糖药。SKF-34288 hydrochloride 抑制 Asn 代谢并导致氨基酸和酰胺的增加。

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SKF-34288 hydrochloride Chemical Structure

SKF-34288 hydrochloride Chemical Structure

CAS No. : 320386-54-7

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Description

SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor. SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway[1]. SKF-34288 hydrochloride inhibits Asn metabolism and results in an increase in amino acids and amides[2].

IC50 & Target

IC50: PEPCK[1]

Molecular Weight

191.64

Formula

C₆H₆ClNO₂S

CAS No.

320386-54-7

SMILES

O=C(C1=NC=CC=C1S)O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
SKF-34288 hydrochloride
目录号:
HY-128923
需求量:

SKF-34288 hydrochloride

Cat. No.: HY-128923