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SWE101 

目录号: HY-126326
产品使用指南

SWE101 (compound 22 b) 是人和大鼠可溶性环氧化物水解酶 (sEH)-P 的有效抑制剂,IC50 分别为 4 μM 和 2.8 μM。SWE101 选择性抑制大鼠 sEH-P,而不抑制小鼠 sEH 的水解酶和磷酸酶活性。

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SWE101 Chemical Structure

SWE101 Chemical Structure

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Description

SWE101 (compound 22 b) is a potent inhibitor of human and rat soluble epoxide hydrolase (sEH)-P, with IC50s of 4 μM and 2.8 μM, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH, while rat sEH-P is selectively impaired[1].

IC50 & Target

IC50: 4 μM (sEH-P of human) and 2.8 μM (sEH-P of rat)[1]

Molecular Weight

376.23

Formula

C₁₉H₁₅Cl₂NO₃

SMILES

O=C(O)CCCC1=NC(C2=CC=C(Cl)C(Cl)=C2)=C(C3=CC=CC=C3)O1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
SWE101
目录号:
HY-126326
需求量:

SWE101

Cat. No.: HY-126326