2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 12-OAHSA

12-OAHSA 是橄榄油的一种成分。12-OAHSA 具有口服活性，可改善胰岛素抵抗肥胖小鼠的葡萄糖稳态。

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12-OAHSA Chemical Structure

12-OAHSA Chemical Structure

CAS No. : 101901-73-9

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12-OAHSA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice[1].

体外研究
(In Vitro)

12-OAHSA (25 μM，24 小时) 抑制 Raw 264.7 巨噬细胞中 LPS 诱导的 IL-1b、IL-6、Nos2 和 Tnf-α[1]。
12-OAHSA (25 μM，6 小时)可降低 Raw 264.7 巨噬细胞中 IKKβ 磷酸化并增加 p65 磷酸化[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

12-OAHSA 相关抗体:
体内研究
(In Vivo)

12-OAHSA (30 mg/kg，口服，持续 10 天) 可抑制 HFD 诱导的肥胖 C57BL/6 小鼠中肥胖诱导的胰岛素抵抗[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 10-week HFD induced obese C57BL/6 mice[1]
Dosage: 30 mg/kg
Administration: p.o., for 10 d
Result: Decreased adipose tissue macrophage (ATMs), and CD4+ and CD8+ T lymphocytes in eWAT.
Inhibits obesity-induced adipose tissue inflammation.
分子量

564.92

Formula

C36H68O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

12-OAHSA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12-OAHSA101901-73-9Endogenous Metaboliteobese miceglucoseinsulinInhibitorinhibitorinhibit

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