2. Apoptosis
  3. Apoptosis
  4. Apomine

Apomine  (Synonyms: SR-45023A; SR 9223i; SK&F-99085)

目录号: HY-19671
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摩尔计算器

Apomine (SR-45023A) 是一种抗肿瘤剂，抑制胆固醇合成中的甲羟戊酸/异戊二烯途径。Apomine 能够加速3-羟基-3-甲基戊二酰辅酶 A 还原酶 (HMGR) 的降解。Apomine 能够抑制包括肺癌、结肠癌、乳腺癌和皮肤癌在内的多种类型癌症细胞的生长。此外，Apomine 还能诱导来源于白血病、结肠癌、肝癌、卵巢癌和乳腺癌的肿瘤细胞系的凋亡 (apoptosis)。

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Apomine Chemical Structure

Apomine Chemical Structure

CAS No. : 126411-13-0

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Apomine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. It can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. In addition, Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer[1].

分子量

562.66

Formula

C28H52O7P2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apomine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apomine126411-13-0SR-45023A SR 9223i SK&F-99085Apoptosislung cancercolon cancerbreast cancerand skin cancerleukemialiver cancerovarian cancerapoptosisInhibitorinhibitorinhibit

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