2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. Bevacizumab (PBS)

Bevacizumab (PBS)  (Synonyms: 贝伐珠单抗 (PBS); Anti-Human VEGF, Humanized Antibody (PBS))

目录号: HY-P9906A 纯度: 96.62%
COA

摩尔计算器

Bevacizumab 是一种人源化的 IgG1 单克隆抗体，高亲和力且特异性地与所有 VEGF-A 结合。

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Bevacizumab (PBS) Chemical Structure

Bevacizumab (PBS) Chemical Structure

CAS No. : 216974-75-3

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规格 价格 是否有货 数量
1 mg ￥1600
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5 mg ￥4900
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10 mg ￥7400
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Other Forms of Bevacizumab (PBS):

Bevacizumab (PBS) 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity[1][2].

体外研究
(In Vitro)

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2[1]. Experimental analysis shows that the EC50 of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC50 value of 0.047±0.0081 μg/mL[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Bevacizumab (PBS) 相关抗体:
体内研究
(In Vivo)

It is demonstrated that the subconjunctival administration of FD006 and Bevacizumab can significantly inhibit CoNV in NaOH cauterized rats compared with the control group (p < 0.01)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

贝伐珠单抗 (PBS)
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 98.94%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Bevacizumab (PBS) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bevacizumab (PBS)216974-75-3Anti-Human VEGF, Humanized Antibody (PBS)贝伐珠单抗 (PBS)VEGFRVascular endothelial growth factor receptorhumanizedvascularendothelialgrowthVEGFeffectivemonoclonalcancerInhibitorinhibitorinhibit

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