2. PROTAC
  3. LYTACs
  4. Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) 

目录号: HY-158033
产品使用指南

摩尔计算器

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) (Compound 24) 是一种甘露糖-6-磷酸酯 (M6Pn)-肽缀合物，能够与多种蛋白质的靶向配体连接，并通过 M6PR 成功地将这些蛋白质内化并降解。Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 可以用于基于 M6Pn 的溶酶体靶向嵌合体 (LYTACs) 的研究。

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Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) Chemical Structure

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) Chemical Structure

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Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Compound 24, Cys modified with M6Pn) is a mannose-6-phosphate (M6Pn)-peptide conjugate capable of binding to targeted ligands of various proteins and successfully internalizing and degrading them through M6PR. Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 can be utilized in the research of lysosomal targeting chimeras (LYTACs) based on M6Pn[1].

IC50 & Target

分子量

3419.55

Formula

C124H230N20O63P6S7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)LYTACsLysosome-targeting chimerasprotein degradationlysosomal targeting chimeras (LYTACs)Inhibitorinhibitorinhibit

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Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn)
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