2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. Callicarboric acid A

NLRP3-IN-27 是 NLRP3 的抑制剂，IC50 值为 0.74 μM。NLRP3 减少 J774A.1 细胞中炎症小体诱导的细胞焦亡。 NLRP3-IN-27 可以从紫珠 Rox 中分离出来。

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Callicarboric acid A Chemical Structure

Callicarboric acid A Chemical Structure

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Callicarboric acid A 相关抗体

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  • 生物活性

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生物活性

NLRP3-IN-27 (compound 1) is an inhibitor of NLRP3 with an IC50 value of 0.74 μM. NLRP3 reduces inflammasome-induced pyroptosis in J774A.1 cells. NLRP3-IN-27 can be isolated from Callicarpa arborea Rox[1].

分子量

320.42

Formula

C19H28O4
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Callicarboric acid A 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Callicarboric acid ANOD-like Receptor (NLR)NLRP3 InhibitorInhibitorinhibitorinhibit

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