1. NF-κB
    PI3K/Akt/mTOR
    Epigenetics
  2. NF-κB
    AMPK
  3. Demethyleneberberine

Demethyleneberberine 

目录号: HY-N0592
产品使用指南

Demethyleneberberine 是一种天然线粒体靶向抗氧化剂。Demethyleneberberine 通过抑制 NF-κB 通路和调节 Th 细胞的平衡来减轻小鼠结肠炎并抑制炎症反应。Demethyleneberberine 可作为 AMPK 激活剂,用于治疗非酒精性脂肪性肝病 (NAFLD)。

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Demethyleneberberine Chemical Structure

Demethyleneberberine Chemical Structure

CAS No. : 25459-91-0

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Description

Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD)[1][2][3].

Molecular Weight

324.35

Formula

C₁₉H₁₈NO₄+

CAS No.

25459-91-0

SMILES

COC1=C(OC)C2=C[N+]3=C(C4=CC(O)=C(O)C=C4CC3)C=C2C=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

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The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Demethyleneberberine
目录号:
HY-N0592
需求量:

Demethyleneberberine

Cat. No.: HY-N0592