Dihydrotachysterol  (Synonyms: 双氢速甾醇；双氢速变固醇)

Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) ^[1][2].

Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue^[1].
Dihydrotachysterol also increases renal phosphate excretion^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

398.66

C₂₈H₄₆O

67-96-9

固体

White to off-white

双氢速甾醇；双氢速变固醇

Room temperature in continental US; may vary elsewhere.

• [1]. I Quack, et al. Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review. Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):376-80.  [Content Brief]

  [2]. M E Peterson, et al. Idiopathic hypoparathyroidism in five cats. J Vet Intern Med. Jan-Feb 1991;5(1):47-51.  [Content Brief]