1. PROTAC Autophagy
  2. Autophagy Ligands for E3 Ligase
  3. Thalidomide-O-C4H4-N(Me)-piperidine-C-boc

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc 

目录号: HY-161192
产品使用指南

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc 是 E3 连接酶配体与连接子的缀合物 (E3 Ligase Ligand-Linker Conjugates),由 Thalidomide (HY-14658) 和对应 Linker 构成。Thalidomide-O-C4H4-N(Me)-piperidine-C-boc 可作为 Cereblon 配体募集 CRBN 蛋白,并作为关键中间体进行完整 PROTACs 分子合成。

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Thalidomide-O-C4H4-N(Me)-piperidine-C-boc Chemical Structure

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc Chemical Structure

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查看 Ligands for E3 Ligase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

IC50 & Target

Cereblon (CRBN)[1]

分子量

554.63

Formula

C29H38N4O7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Thalidomide-O-C4H4-N(Me)-piperidine-C-boc 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thalidomide-O-C4H4-N(Me)-piperidine-C-boc
目录号:
HY-161192
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