2. Gene
  3. ROS1 - ROS proto-oncogene 1, receptor tyrosine kinase Gene

ROS1 - ROS proto-oncogene 1, receptor tyrosine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：ROS 原癌基因1 ， 受体酪氨酸激酶

种属: Sus scrofa

基因 ID: 100156931 | 基因类型: protein coding

关于 ROS1

Primary_assembly 1: 44,410,351-44,534,874 forward strand.Sscrofa11.1:CM000812.5

This gene has 1 transcript (splice variant), 125 orthologues and 52 paralogues. Biased expression in lung (RPKM 3.1), mixtures (RPKM .5) and 3 other tissues.

ROS1 基因产物(9)

mRNA Protein Name
XM_021089103.1 XP_020944762.1 proto-oncogene tyrosine-protein kinase ROS isoform X4
XM_021089113.1 XP_020944772.1 proto-oncogene tyrosine-protein kinase ROS isoform X6
XM_021089094.1 XP_020944753.1 proto-oncogene tyrosine-protein kinase ROS isoform X2
XM_021089108.1 XP_020944767.1 proto-oncogene tyrosine-protein kinase ROS isoform X5
XM_021089087.1 XP_020944746.1 proto-oncogene tyrosine-protein kinase ROS isoform X1
XM_021089102.1 XP_020944761.1 proto-oncogene tyrosine-protein kinase ROS isoform X3
XM_021089132.1 XP_020944791.1 proto-oncogene tyrosine-protein kinase ROS isoform X9
XM_021089129.1 XP_020944788.1 proto-oncogene tyrosine-protein kinase ROS isoform X8
XM_021089122.1 XP_020944781.1 proto-oncogene tyrosine-protein kinase ROS isoform X7

ROS1 蛋白结构

FN3

FN3: cd00063 (108 - 193)

FN3

FN3: cd00063 (210 - 289)

FN3

FN3: cd00063 (566 - 662)

FN3

FN3: cd00063 (956 - 1023)

fn3

fn3: pfam00041 (1037 - 1135)

FN3

FN3: smart00060 (1447 - 1529)

FN3

FN3: cd00063 (1553 - 1653)

FN3

FN3: cd00063 (1652 - 1743)

FN3

FN3: cd00063 (1748 - 1837)

PTKc_c-ros

PTKc_c-ros: cd05044 (1945 - 2219)

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  • 2000
  • 2351 a.a.
蛋白主名 其他名称

proto-oncogene tyrosine-protein kinase ROS

c-ros oncogene 1 , receptor tyrosine kinase

相关产品

Approval
生物活性分子 (7)
目录号 产品名 作用方式
纯度 是否罕见病
HY-50878 Crizotinib 99.97% 是
HY-12215 Lorlatinib 99.92% 是
HY-12678 Entrectinib 99.87% 是
HY-W015913 Sodium 2-oxopropanoate Inhibitor 99.86% 是
HY-103022 Repotrectinib Inhibitor 99.90% 否
HY-50878A Crizotinib hydrochloride 99.86% 是
HY-50878B Crizotinib acetate Inhibitor / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-145574 Iruplinalkib Inhibitor 99.29% Phase 3
HY-15514 Merestinib Inhibitor 99.99% Phase 2
HY-131003 Taletrectinib Inhibitor 99.78% Phase 2
HY-15514A Merestinib dihydrochloride Inhibitor 99.36% Phase 2
HY-131003A Taletrectinib free base Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (38)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0578 Apigenin 7-glucoside 98.97% 否
HY-152292 Zidesamtinib Inhibitor 99.55% 否
HY-W015913S Sodium 2-oxopropanoate-13C3 Inhibitor 99.7% 否
HY-155163 APG-2449 Inhibitor 98.83% 否
HY-12678S1 Entrectinib-d8 99.82% 否
HY-50878S Crizotinib-d5 ≥99.0% 否
HY-112801 F-1 Inhibitor 98.65% 否
HY-147413 Unecritinib Inhibitor 98.83% 否
HY-B1106A Tetrahydroxyquinone monohydrate Activator ≥97.0% 否
HY-B1106 Tetrahydroxyquinone ≥98.0% 否
HY-122311 Orniplabin Inhibitor / 否
HY-12678S Entrectinib-d4 Inhibitor / 否
HY-N1306 Sideroxylin / 否
HY-161358 FAK-IN-20 / 否
HY-123454 SKF1 / 否
HY-130794 ALK/ROS1-IN-1 Inhibitor / 否
HY-144697 p38 MAPK-IN-3 / 否
HY-147795 Nampt-IN-8 / 否
HY-150974 ROS1-IN-1 Inhibitor / 否
HY-153743 Protein kinase inhibitor 4 Inhibitor / 否
HY-155178 Antiproliferative agent-34 Inhibitor / 否
HY-156360 Xanthine oxidase-IN-12 Inhibitor / 否
HY-157391 ALK/ROS1-IN-3 Inhibitor / 否
HY-157437 AChE/BChE-IN-16 Inhibitor / 否
HY-158016 Antiproliferative agent-49 / 否
HY-162311 Anticancer agent 194 / 否
HY-162488 Laccase-IN-3 Inhibitor / 否
HY-163280 JGB-1-155 Activator / 否
HY-N11887 Linocinnamarin Inhibitor / 否
HY-N2693 6,8-Diprenylorobol / 否
HY-N7798 Pennogenin 98.69% 否
HY-RS12135 ROS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12136 Ros1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12137 ROS1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160172 ALK/ROS1-IN-4 Inhibitor / 否
HY-160172A ALK/ROS1-IN-4 hydrate Inhibitor / 否
HY-50878AS Crizotinib-d9 hydrochloride / 否
HY-111416 WY-135 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ROS1 NCBI NCBI:6098
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