Cd28 - CD28 antigen Gene

中文名称：CD28 抗原

种属: Mus musculus

关于 Cd28

功能概要

该基因编码的蛋白可启动蛋白激酶结合活性。作用于多个过程的上游或内部，包括免疫反应的正向调节；细胞内信号转导的正向调节；和淋巴细胞活化的调节。位于质膜和免疫突触的外侧。该基因的人类直系同源物与多发性硬化症和 1 型糖尿病有关。与人 CD28（CD28 分子）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase binding activity. Acts upstream of or within several processes, including positive regulation of immune response; positive regulation of intracellular signal transduction; and regulation of lymphocyte activation. Located in external side of plasma membrane and immunological synapse. Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus. Orthologous to human CD28 (CD28 molecule). [provided by Alliance of Genome Resources, Apr 2022]