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  2. Ctse - cathepsin E Gene

Ctse - cathepsin E Gene

中文名称:组织蛋白酶 E

种属: Rattus norvegicus

同用名: CEA; CEB; Ctsea

基因 ID: 25424 | 基因类型: protein coding

关于 Ctse

Primary_assembly 13: 43,092,128-43,114,502 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 142 orthologues, 8 paralogues and is associated with 7 phenotypes. Biased expression in Spleen (RPKM 389.2), Thymus (RPKM 338.8) and 2 other tissues.

功能概要

该基因编码的蛋白可启动天冬氨酸型内肽酶活性。通过 MHC II 类和蛋白质自动加工参与抗原加工和外源肽抗原的呈递。位于核内体。与人类 CTSE(组织蛋白酶 E)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables aspartic-type endopeptidase activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class II and protein autoprocessing. Located in endosome. Orthologous to human CTSE (Cathepsin E). [provided by Alliance of Genome Resources, Apr 2022]

Ctse 基因产物(2)

mRNA Protein Name
NM_012938.2 NP_037070.2 cathepsin E isoform 1 precursor
NM_001401267.1 NP_001388196.1 cathepsin E isoform 2 preproprotein

Ctse 蛋白结构

A1_Propeptide

A1_Propeptide: pfam07966 (22 - 50)

pepsin_retropepsin_like

pepsin_retropepsin_like: cl11403 (79 - 394)

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  • 398 a.a.
蛋白主名 其他名称

cathepsin E

重组 Ctse 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74344 Cathepsin E Protein, Rat (HEK293, His) AAH62002 (M1-P398) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ctse NCBI NCBI:1510
Mus musculus Ctse NCBI NCBI:13034