2. Stem Cell/Wnt Epigenetics TGF-beta/Smad Cytoskeleton Cell Cycle/DNA Damage
  3. PKA PKC Myosin ROCK
  4. HA-100 hydrochloride

HA-100 hydrochloride 是一种有效的蛋白激酶抑制剂，抑制 PKG，PKA，PKC 和 MLC 激酶的 IC50 值分别为 4 μM、8 μM、12 μM 和 240 μM。HA-100 hydrochloride 也用作 ROCK 抑制剂。

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HA-100 hydrochloride Chemical Structure

HA-100 hydrochloride Chemical Structure

CAS No. : 141543-63-7

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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HA-100 hydrochloride 的其他形式现货产品:

Customer Review

Other Forms of HA-100 hydrochloride:

HA-100 hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 PKC 亚型特异性产品:

查看所有亚型
PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKCι

查看 ROCK 亚型特异性产品:

查看所有亚型
ROCK ROCK1 ROCK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HA-100 hydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 hydrochloride also used as a ROCK inhibitor[1][2].

IC50 & Target[1]

PKG

4 μM (IC50)

PKA

8 μM (IC50)

PKC

12 μM (IC50)

MLCK

240 μM (IC50)

ROCK

 

体外研究
(In Vitro)

HA-100 hydrochloride inhibits MLC-kinase and PKC competitively with respect to ATP, with Kis of 61 and 6.5 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HA-100 hydrochloride 相关抗体:
分子量

313.80

Formula

C13H16ClN3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HA-100 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HA-100141543-63-7HA100HA 100PKAPKCMyosinROCKProtein kinase AProtein kinase CRho-associated protein kinaseRho-associated kinaseRho-kinaseROKproteinkinaseMLCKPKGInhibitorinhibitorinhibit

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产品名称：
HA-100 hydrochloride
目录号：
HY-100984A
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