1. Cell Cycle/DNA Damage Epigenetics
  2. HDAC
  3. HDAC6-IN-8

通过修饰Cap基团设计并合成了多种化合物,通过酶抑制试验表明,化合物12c发挥了广谱酶抑制活性,化合物9m和9q更倾向于抑制HDAC6,在代表性亚型中表现出一定的选择性抑制活性。

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HDAC6-IN-8 Chemical Structure

HDAC6-IN-8 Chemical Structure

CAS No. : 2796282-49-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A variety of compounds were designed and synthesized by modifying cap groups. The enzyme inhibition test showed that compound 12C had broad-spectrum enzyme inhibitory activity, and compounds 9m and 9q were more inclined to inhibit HDAC6, showing a certain selective inhibitory activity among the representative subtypes.

分子量

510.32

Formula

C23H17BrFN5O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

HDAC6-IN-8 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HDAC6-IN-8
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HY-147730
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