2. Others Apoptosis PI3K/Akt/mTOR Immunology/Inflammation NF-κB MAPK/ERK Pathway GPCR/G Protein Metabolic Enzyme/Protease Neuronal Signaling
  3. Akt p38 MAPK Histamine Receptor Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
  4. Histamine-13C5

Histamine-13C5  (Synonyms: Ergamine-13C5)

目录号: HY-B1204S3
产品使用指南 技术支持

Histamine-13C5 是一种 13C 标记的 Histamine (HY-B1204)。Histamine 是组胺受体 (histamine receptor) 激动剂和血管扩张剂。Histamine 是一种有机氮化合物，参与局部免疫反应，调节肠道生理功能，并作为神经递质发挥作用。Histamine 影响 p38 MAPK/Akt 信号通路，具有抗肿瘤、抗氧化和抗炎活性。Histamine 可用于急性髓系白血病、恶性黑色素瘤和肾细胞癌的研究。

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Histamine-<sup>13</sup>C<sub>5</sub>

Histamine-13C5 Chemical Structure

CAS No. : 2897532-68-0

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Other Forms of Histamine-13C5:

Histamine-13C5 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

查看 p38 MAPK 亚型特异性产品:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Histamine-13C5 is the 13C labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma[1][2][3][4][5][6][7].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Histamine-13C5 相关抗体:
分子量

116.11

Formula

13C5H9N3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Histamine-13C5 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Histamine-13C52897532-68-0Ergamine-13C5Aktp38 MAPKHistamine ReceptorIsotope-Labeled CompoundsReactive Oxygen Species (ROS)Endogenous MetaboliteApoptosisPKBProtein kinase Banalytical standardorganic nitrogenimmune responsesintestinal physiological functionsneurotransmitterInhibitorinhibitorinhibit

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