2. Apoptosis Immunology/Inflammation
  3. TNF Receptor Interleukin Related
  4. Isoforskolin

Isoforskolin  (Synonyms: Coleonol B)

目录号: HY-N6927 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Isoforskolin 是原产于中国的 C. forskohlii 的主要活性成分。在人单核白细胞中，Isoforskolin 减少了脂多糖 (LPS) 诱导的细胞因子如 TNF-α，IL-1β，IL-6 和 IL-8 的分泌。Isoforskolin 可作为抗炎剂，有潜力用于莱姆关节炎的研究。

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Isoforskolin Chemical Structure

Isoforskolin Chemical Structure

CAS No. : 64657-21-2

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规格 价格 是否有货 数量
1 mg ￥1200
In-stock
5 mg ￥3000
In-stock
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50 mg   询价  

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Isoforskolin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].

IC50 & Target

IL-1β

 

IL-6

 

IL-8

 

体外研究
(In Vitro)

Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Isoforskolin 相关抗体:
分子量

410.50

Formula

C22H34O7
CAS 号
性状

固体

颜色

White to off-white

中文名称

异佛司可林；异佛斯可林
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Isoforskolin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoforskolin64657-21-2Coleonol B异佛司可林异佛斯可林TNF ReceptorInterleukin RelatedTumor Necrosis Factor ReceptorTNFRILTNF-αIL-1βIL-6 and IL-8LymearthritisInhibitorinhibitorinhibit

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