2. 诱导疾病模型产品 GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. 神经系统疾病模型 Dopamine Receptor Endogenous Metabolite
  4. 帕金森综合症模型
  5. L-DOPA sodium

L-DOPA sodium  (Synonyms: Levodopa sodium; 3,4-Dihydroxyphenylalanine sodium)

目录号: HY-N0304A
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摩尔计算器

L-DOPA (Levodopa) sodium 是一种具有口服活性的神经递质多巴胺的代谢前体。L-DOPA sodium 可以透过血脑屏障，并在大脑中转化为多巴胺。L-DOPA sodium 具有抗痛觉过敏作用，可用于帕金森氏病的研究。

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L-DOPA sodium Chemical Structure

L-DOPA sodium Chemical Structure

CAS No. : 63302-01-2

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L-DOPA sodium 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA sodium can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA sodium has anti-allodynic effects, and can be used for Parkinson's disease research[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

L-DOPA sodium (20 mg/kg; orally) reduces Rotenone-induced motor dysfunction[3].
L-DOPA sodium (0-100 mg/kg; orally) reverses tactile, cold and heat allodynia in neuropathic rat without any side effect in sprague-Dawley rats[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J mice (7-week-old)[3]
Dosage: 20 mg/kg
Administration: Orally
Result: Reduced Rotenone-induced motor dysfunction.
Animal Model: Sprague-Dawley rats[4]
Dosage: 10, 30, 50, 70, and 100 mg/kg
Administration: Orally
Result: Reverses tactile, cold and heat allodynia in neuropathic rat without any side effect.
Clinical Trial
分子量

219.17

Formula

C9H10NNaO4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-DOPA sodium 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

L-DOPA63302-01-2Levodopa3,4-DihydroxyphenylalanineDopamine ReceptorEndogenous MetaboliteOrallyprecursorneurotransmittersdopamineblood-brainbarrieranti-allodynicParkinsonInhibitorinhibitorinhibit

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