1. Apoptosis Membrane Transporter/Ion Channel Anti-infection Metabolic Enzyme/Protease Neuronal Signaling Others
  2. Bacterial Endogenous Metabolite Apoptosis iGluR Isotope-Labeled Compounds
  3. Linalool-d6

Linalool-d6  (Synonyms: 芳樟醇-d6)

目录号: HY-N0368S2
产品使用指南

Linalool-d6 是氘代标记的 Trans-Anethole (HY-N0367)。Trans-Anethole ((E)-Anethole) 是从 Foeniculum vulgare 分离得到的一种苯丙烯衍生物,在肿瘤细胞系中,低浓度下有雌激素活性,而在高浓度下具有细胞毒性。Trans-Anethole ((E)-Anethole) 是茴香、桃金娘、甘草、樟脑等植物中重要气味的组成部分。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Linalool-d<sub>6</sub> Chemical Structure

Linalool-d6 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

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规格 是否有货
1 mg 询价

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Other Forms of Linalool-d6:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Linalool-d6 is deuterated labeled Trans-Anethole (HY-N0367). Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Foeniculum vulgare, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines[1][2]. Trans-Anethole ((E)-Anethole) contributes a large component of the odor and flavor of anise and fennel, anise myrtle, liquorice, camphor, magnolia blossoms, and star anise[3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]
Linalool (0-2000 μM, 24-72 h) 可以通过氧化应激诱导癌细胞 (U87-MG,HepG-2,SW620 and so on) 凋亡,同时保护正常细胞 PC12[4]
Linalool (0-2000 mg/mL, 0-72 h) 通过破坏细胞膜发挥抗菌作用[4]
Linalool (0-2 mM, 24-48 h) 通过诱导 G0/G1 和/或 G2/M 细胞周期停滞来抑制 A549 细胞增殖,而不影响正常肺 WI-38 细胞的细胞活力。Linalool 抑制 A549 细胞迁移[5]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Linalool (每隔 1 天口服 150,200,250 mg/kg,持续 21 天) 使 S-180 实体瘤小鼠模型的肿瘤生长降低 50%,在正常肝脏中抑制氧化,在肿瘤组织中促进氧化[6]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

160.29

Formula

C10H12D6O

非标记 CAS

78-70-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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