1. Immunology/Inflammation
  2. NOD-like Receptor (NLR)
  3. JT001 sodium

JT001 sodium  (Synonyms: NLRP3-IN-19 sodium)

目录号: HY-156034A
产品使用指南

JT001 (NLRP3-IN-19) sodium 是一种有效,特异性和具有口服活性的 NLRP3 抑制剂。 JT001 sodium 可以抑制 NLRP3 炎症小体的组装,从而抑制细胞因子的释放并预防细胞焦亡。 JT001 sodium 可用于非酒精性脂肪性肝炎和肝纤维化的研究。

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JT001 sodium Chemical Structure

JT001 sodium Chemical Structure

CAS No. : 2238820-09-0

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Other Forms of JT001 sodium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JT001 (NLRP3-IN-19) sodium is a potent, specific and orally active inhibitor of NLRP3. JT001 sodium can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 sodium can be used for the research of nonalcoholic steatohepatitis and liver fibrosis[1].

IC50 & Target[1]

NLRP3

 

分子量

425.46

Formula

C19H22N4NaO4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
JT001 sodium
目录号:
HY-156034A
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