2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor Adrenergic Receptor 5-HT Receptor
  4. Platelet aggregation-IN-3

Platelet aggregation-IN-3 (Compound 5) 是 H2 histamine receptors、α2(A,C)--肾上腺素能受体 (α2-AR) 和 5-HT2(B,C) serotonin receptors 的配体。Platelet aggregation-IN-3 可以抑制 ADP 和胶原诱导的血小板聚集，也可以调节肿瘤细胞诱导的血小板聚集 (TCIPA)。Platelet aggregation-IN-3 有望用于心血管疾病抗血小板治疗及预防癌症相关血栓形成和肿瘤转移的研究。

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Platelet aggregation-IN-3 Chemical Structure

Platelet aggregation-IN-3 Chemical Structure

CAS No. : 1029802-21-8

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Platelet aggregation-IN-3 相关抗体

Top Publications Citing Use of Products

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

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α adrenergic receptor β adrenergic receptor

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5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

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生物活性

Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis[1].

IC50 & Target

H2 Receptor

 

5-HT2B Receptor

 

α2-adrenergic receptor

 

Histamine Receptor

 

分子量

251.76

Formula

C13H18ClN3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Platelet aggregation-IN-3 相关分类

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Keywords:

Platelet aggregation-IN-31029802-21-8Histamine ReceptorAdrenergic Receptor5-HT ReceptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorH2 histamine receptorsα2-AR5-HT2(B,C) serotonin receptorscancer-related thrombosis and tumour metastasisInhibitorinhibitorinhibit

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