1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Prostaglandin H1

Prostaglandin H1  (Synonyms: PGH1)

目录号: HY-126819
产品使用指南

Prostaglandin H1 (PGH1),DGLA 的环氧化酶代谢物,也是一种 CRTh2 激动剂以及 1 系列抗炎前列腺素的前体物质。Prostaglandin H1 可用于炎症的研究。

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Prostaglandin H1 Chemical Structure

Prostaglandin H1 Chemical Structure

CAS No. : 52589-22-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Prostaglandin H1 (PGH1), the cyclooxygenase metabolite of DGLA, is also a CRTh2 agonist and precursor for the anti-inflammatory prostaglandins of the 1-series. Prostaglandin H1 can be used in the study of inflammation[1].

IC50 & Target

CRTh2[1].

体外研究
(In Vitro)

Prostaglandin H1 (0-10 μM; 60 min) 通过 CRTH2 激活人类 Th2 细胞[1]
Prostaglandin H1 通过 CRTH2 诱导人嗜酸性粒细胞 Ca2+ 动员[1]
Prostaglandin H1 (1 µM; 10 min) 在流动条件下诱导嗜酸性粒细胞粘附人肺微血管内皮细胞[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Th2 cells
Concentration: 0-10 μM
Incubation Time: 60 min
Result: Induced Th2 cells migration.
分子量

354.48

Formula

C20H34O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Prostaglandin H1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Prostaglandin H1
目录号:
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