2. PROTAC Metabolic Enzyme/Protease
  3. PROTACs Glutaminase
  4. PROTAC TG2 degrader-1

PROTAC TG2 degrader-1（化合物 11）是一种基于 von Hippel-Lindau (VHL) 的 PROTAC，靶向组织转谷氨酰胺酶 (TG2)，KD 为 68.9 μM。PROTAC TG2 degrader-1 以蛋白酶体依赖性方式降低卵巢癌细胞中的 TG2。

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PROTAC TG2 degrader-1 Chemical Structure

PROTAC TG2 degrader-1 Chemical Structure

CAS No. : 3033465-55-0

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PROTAC TG2 degrader-1 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

查看所有亚型
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC TG2 degrader-1 (compound 11) is a von Hippel-Lindau (VHL)-based PROTAC targeting tissue transglutaminase (TG2) with a KD of 68.9 μM. PROTAC TG2 degrader-1 reduces TG2 in ovarian cancer cells in a proteasome-dependent manner[1].

IC50 & Target[1]

VHL

 

分子量

1052.29

Formula

C55H73N9O10S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PROTAC TG2 degrader-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC TG2 degrader-13033465-55-0PROTACsGlutaminasePROTACTissue TransglutaminaseTG2PEG5 linkerproteasomeInhibitorinhibitorinhibit

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产品名称：
PROTAC TG2 degrader-1
目录号：
HY-155643
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