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(Rac)-BMS-816336 

目录号: HY-101930A
产品使用指南

(Rac)-BMS-816336 (Compound 6n) 是 BMS-816336 的外消旋体。(Rac)-BMS-816336 是一种有效的人和小鼠 11β-羟类固醇脱氢酶 1 型 (11β-HSD1) 抑制剂,其 IC50 分别为 10 nM 和 68 nM,并具有良好的代谢稳定性 。

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(Rac)-BMS-816336 Chemical Structure

(Rac)-BMS-816336 Chemical Structure

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规格 价格 是否有货
5 mg ¥3500
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10 mg ¥5500
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50 mg ¥16500
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100 mg ¥26500
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  • 生物活性

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  • 参考文献

生物活性

(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with IC50s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability[1].

IC50 & Target

IC50: 10 nM (Human 11β-HSD1) and 68 nM (Mouse 11β-HSD1)[1]

体内研究
(In Vivo)

(Rac)-BMS-816336 (compound 6n) has good metabolic stability, and the remaining rates in human, mouse and rats of 88%,82% and 72%, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

341.44

Formula

C21H27NO3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
(Rac)-BMS-816336
目录号:
HY-101930A
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