2. Others Neuronal Signaling Cell Cycle/DNA Damage
  3. Topoisomerase Isotope-Labeled Compounds Cholinesterase (ChE)
  4. RPR121056-d3

RPR121056-d3 是 RPR121056 的氘代物。RPR121056 是 Irinotecan (HY-16562) 的代谢产物，由 CYP3A4 产生。Irinotecan 是一种抗肿瘤剂，可抑制 I 型拓扑异构酶，导致细胞死亡，并广泛用于治疗结直肠癌。Irinotecan 也能直接抑制乙酰胆碱酯酶 (AChE)。

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RPR121056-d3 Chemical Structure

RPR121056-d3 Chemical Structure

CAS No. : 1217816-76-6

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规格 是否有货
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Other Forms of RPR121056-d3:

RPR121056-d3 相关抗体

Top Publications Citing Use of Products

查看 Topoisomerase 亚型特异性产品:

查看所有亚型
Topoisomerase Topo I Topo II

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RPR121056-d3 is the deuterium labeled RPR121056. RPR121056 is a metabolite of Irinotecan (HY-16562), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1][2].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RPR121056-d3 相关抗体:
分子量

621.70

Formula

C33H35D3N4O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RPR121056-d3 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RPR121056-d31217816-76-6TopoisomeraseIsotope-Labeled CompoundsCholinesterase (ChE)Inhibitorinhibitorinhibit

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目录号：
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