1. Cell Cycle/DNA Damage
  2. CDK
  3. Ryuvidine

Ryuvidine 是一种含有的 SET 结构域的蛋白质 8 (SETD8) 的有效抑制剂,其 IC50 为 0.5 µM,并在体外抑制 H4K20 的甲基化。Ryuvidine 还抑制 CDK4IC50 为 6.0 μM,并对一系列人类癌细胞具有细胞毒性。

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Ryuvidine Chemical Structure

Ryuvidine Chemical Structure

CAS No. : 265312-55-8

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1 mg ¥693
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ryuvidine is a potent inhibitor of SET domain-containing protein 8(SETD8) with an IC50 of 0.5 µM and suppresses monomethylation of H4K20 in vitro[1]. Ryuvidine also inhibits CDK4 with an IC50 of 6.0 μM and is cytotoxic against a range of human cancer cells[2].

IC50 & Target

CDK4

6.0 μM (IC50)

分子量

284.33

Formula

C15H12N2O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Ryuvidine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ryuvidine
目录号:
HY-100624
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