2. Immunology/Inflammation
  3. Interleukin Related
  4. Secukinumab

Secukinumab  (Synonyms: 司库奇尤单抗; AIN457)

目录号: HY-P9927 纯度: 98.10%
COA

摩尔计算器

Secukinumab (AIN457) 是一种针对白细胞介素 (IL-17A) 的高亲和力单克隆抗体。Secukinumab (AIN457) 是首创的抗 IL-17 剂，用于研究斑块状银屑病、强直性脊柱炎和银屑病关节炎。

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Secukinumab Chemical Structure

Secukinumab Chemical Structure

CAS No. : 1229022-83-6

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规格 价格 是否有货 数量
1 mg ￥1600
In-stock
5 mg ￥5600
In-stock
10 mg ￥8680
In-stock
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100 mg   询价  

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Secukinumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis[1][2].

IC50 & Target[1]

IL-17A

 

体外研究
(In Vitro)

Secukinumab 是一种全人源单克隆抗体，可选择性结合并中和白细胞介素 17A[2]。
Secukinumab (1 nM、10 nM 和 100 nM) 可抑制 IL17A 和 IL17A/TNF a-诱导人星形胶质细胞中 IL6 蛋白水平的增加[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Secukinumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

苏金单抗；司库奇尤单抗
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥99.20%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Secukinumab 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Secukinumab1229022-83-6AIN457苏金单抗司库奇尤单抗AIN 457AIN-457Interleukin RelatedILpsoriasisfirst-in-classselectiveneutralizesinterleukinarthritisInhibitorinhibitorinhibit

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