2. Immunology/Inflammation Apoptosis
  3. NO Synthase COX Interleukin Related TNF Receptor
  4. Shizukaol B

Shizukaol B 是一种椴树烷型二聚倍半萜类化合物，曾从青牡丹 (Chloranthus henryi) 全株中分离得到。Shizukaol B 对脂多糖 (LPS) 诱导的 BV2 微胶质细胞活化具有抗炎作用。Shizukaol B 抑制诱导型一氧化氮合酶 (iNOS) 和 COX-2，还抑制 NO 产生，和 TNF-α、IL-1β 表达。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Shizukaol B Chemical Structure

Shizukaol B Chemical Structure

CAS No. : 142279-40-1

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Shizukaol B 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression[1].

IC50 & Target[1]

COX-2

 

iNOS

 

IL-1β

 

体外研究
(In Vitro)

Shizukaol B (25 μM; 0-60 min) 抑制 LPS (1 μg/mL; 0-60 min) 介导的 c-Jun N 末端激酶 1/2 (JNK) 激活，不影响 ERK1/2 或 p38 磷酸化[1]。
Shizukaol B (12.5-50 μM; 4 h) 抑制 LPS 诱导 (1 μg/mL; 24 h) 的 NO 生成，抑制 iNOS 和 COX-2 的表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Shizukaol B 相关抗体:
分子量

732.77

Formula

C40H44O13
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Shizukaol B 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Shizukaol B142279-40-1NO SynthaseCOXInterleukin RelatedTNF ReceptorNitric oxide synthasesNOSCyclooxygenaseILTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Shizukaol B
目录号：
HY-N8371
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.