1. Others NF-κB Autophagy Apoptosis Anti-infection
  2. Isotope-Labeled Compounds NF-κB Autophagy Apoptosis Ferroptosis Bacterial Antibiotic
  3. Sulfasalazine-d4

Sulfasalazine-d4  (Synonyms: 柳氮磺吡啶 d4)

目录号: HY-14655S 纯度: ≥99.0%
COA 产品使用指南

Sulfasalazine-d4 是 Sulfasalazine 的氘代物。Sulfasalazine (NSC 667219) 常用于类风湿关节炎和溃疡性结肠炎的相关研究。Sulfasalazine 可抑制 NF-κB 的活性。Sulfasalazine 是 type 1 的铁死亡 (ferroptosis) 诱导剂。

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Sulfasalazine-d<sub>4</sub> Chemical Structure

Sulfasalazine-d4 Chemical Structure

CAS No. : 1346606-50-5

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1 mg ¥2500
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulfasalazine-d4 is the deuterium labeled Sulfasalazine. Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer[1][2][3][4].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

402.42

Formula

C18H10D4N4O5S

CAS 号
性状

固体

颜色

White to off-white

中文名称

柳氮磺吡啶 d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
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目录号:
HY-14655S
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