2. Peptides
  3. Vasomera

Vasomera 是一种稳定的长效血管活性肠肽 (VIP) 激动剂。Vasomera 作用于 G 蛋白偶联的 VPAC2 受体。Vasomera 可用于与肌营养不良症相关的心肌病的研究。

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Custom Peptide Synthesis

Vasomera Chemical Structure

Vasomera Chemical Structure

CAS No. : 1416067-68-9

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Vasomera 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Vasomera is a stable long-acting vasoactive intestinal peptide (VIP) agonist. Vasomera acts on the G-protein-coupled VPAC2-receptors. Vasomera can be used for the research of cardiomyopathy associated with dystrophinopathies[1].

体内研究
(In Vivo)

Vasomera (i.v.; 7.5 μg/kg/min; single) improves arterial elastance and ventriculo-arterial coupling and improves indices of diastolic function (i.e., lusitropy) in animals with chronic renoprival hypertension mimicking heart failure with preserved ejection fraction (HFpEF)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats[1]
Dosage: 7.5 μg/kg
Administration: IV, 7.5 μg/kg/min, single
Result: Decreased the estimated arterial elastance, improved ventriculo-arterial coupling, reduced filling pressures, accelerated the time-constant of relaxation and improved compliance.
Clinical Trial
CAS 号
运输条件

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纯度 & 产品资料
参考文献

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vasomera1416067-68-9Otherslong-actingvasoactive intestinal peptide (VIP)G-proteindystrophinopathiesInhibitorinhibitorinhibit

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