2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. 5-Iodoresiniferatoxin

5-Iodoresiniferatoxin  (Synonyms: I-RTX)

目录号: HY-108453
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摩尔计算器

5-Iodoresiniferatoxin (I-RTX) 是一种选择性的 TRPV1 拮抗剂，对大鼠和人类受体的 IC50 分别为 0.7 和 5.4 nM。5-Iodoresiniferatoxin 会在体内诱导 TRPV1 依赖性低温。

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5-Iodoresiniferatoxin Chemical Structure

5-Iodoresiniferatoxin Chemical Structure

CAS No. : 535974-91-5

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5-Iodoresiniferatoxin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-Iodoresiniferatoxin (I-RTX) is a selective TRPV1 antagonist, with an IC50s of 0.7 and 5.4 nM for rat and human receptors, respectively. 5-Iodoresiniferatoxin induces TRPV1-dependent hypothermia in vivo[1].

IC50 & Target[1]

rTRPV1

0.7 nM (IC50)

hTRPV1

5.4 nM (IC50)

分子量

754.60

Formula

C37H39IO9
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-Iodoresiniferatoxin 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Iodoresiniferatoxin535974-91-5I-RTXTRP ChannelTransient receptor potential channelshypothermiaInhibitorinhibitorinhibit

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