2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. ABP 215

ABP 215 (Bevacizumab-awwb) 是一种 Bevacizumab (Bevacizumab (HY-P9906)) 生物类似药，是一种靶向 VEGFA (VEGFR) 的人源化 IgG1 单克隆抗体。ABP 215 具有抗癌作用，可用于转移性结直肠癌 (mCRC) 研究。

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ABP 215

ABP 215 Chemical Structure

CAS No. : 1438851-35-4

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规格 是否有货
1 mg 询价
5 mg 询价

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ABP 215 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ABP 215 (Bevacizumab-awwb), a Bevacizumab (Bevacizumab (HY-P9906)) biosimilar, is a humanized IgG1 monoclonal antibody targeting VEGFA (VEGFR). ABP 215 has anticancer effects, and can be used metastatic colorectal cancer (mCRC) research[1][2].

体外研究
(In Vitro)

ABP 215 (Bevacizumab-awwb) 与 VEGF-A 结合，阻止 VEGF-A 与内皮细胞表面的 VEGF 受体结合，抑制内皮细胞增殖和新血管形成，从而导致肿瘤脉管系统正常化。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ABP 215 相关抗体:
Clinical Trial
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ABP 215 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ABP 2151438851-35-4ABP215ABP-215VEGFRVascular endothelial growth factor receptorVEGFAmetastatic colorectal cancerBevacizumab biosimilaranticancer effectInhibitorinhibitorinhibit

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产品名称：
ABP 215
目录号：
HY-P99476
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