1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. Aflibercept (VEGF Trap)

Aflibercept (VEGF Trap) 

目录号: HY-108801A 纯度: 97.66%
COA

Aflibercept (VEGF Trap) 是由 VEGFR1 和 VEGFR2 的 Ig 结构域与人 IgG1 的 Fc 域融合而成的可溶性诱饵 VEGFR。Aflibercept 抑制 VEGF 信号通过抑制 VEGF 参与调控的通路。Aflibercept 可以用于老年性黄斑变性 (AMD) 和心血管疾病的研究。

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Aflibercept (VEGF Trap) Chemical Structure

Aflibercept (VEGF Trap) Chemical Structure

CAS No. : 862111-32-8

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Other Forms of Aflibercept (VEGF Trap):

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease[1][2][3].

种属

Human

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Aflibercept (VEGF Trap) 相关分类

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  • 稀释计算器

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质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Aflibercept (VEGF Trap)
目录号:
HY-108801A
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