1. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Histamine Receptor Endogenous Metabolite
  3. Diphenhydramine-d6 hydrochloride

Diphenhydramine-d6 hydrochloride  (Synonyms: 盐酸苯海拉明 d6 (盐酸盐))

目录号: HY-B0303AS 纯度: 98.83%
COA 产品使用指南

Diphenhydramine-d6 (hydrochloride) 是 Diphenhydramine hydrochloride 的氘代物。Diphenhydramine hydrochloride 是第一代具有抗胆碱能作用的组胺 H1 受体 (histamine H1-receptor) 拮抗剂。Diphenhydramine hydrochloride 能透过血脑屏障。

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Diphenhydramine-d<sub>6</sub> hydrochloride Chemical Structure

Diphenhydramine-d6 hydrochloride Chemical Structure

CAS No. : 1189986-72-8

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5 mg ¥1900
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Other Forms of Diphenhydramine-d6 hydrochloride:

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].

IC50 & Target

H1 Receptor

 

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

297.85

Formula

C17H16D6ClNO

CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸苯海拉明 d6 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Diphenhydramine-d6 hydrochloride
目录号:
HY-B0303AS
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