2. Immunology/Inflammation
  3. IFNAR
  4. Emapalumab

Emapalumab  (Synonyms: NI-0501)

目录号: HY-P99191 纯度: 98.86%
COA

摩尔计算器

Emapalumab (NI-0501) 是一种人源 IgG1 单克隆抗体，可非竞争性地抑制 IFN-γ。Emapalumab 与游离的 IFN-γ 以及与其受体结合的 IFN-γ 具有高亲和力 (Kd=1.4 pM)。Emapalumab 可用于噬血细胞性淋巴组织细胞增多症 (HLH) 的研究。

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Emapalumab Chemical Structure

Emapalumab Chemical Structure

CAS No. : 1709815-23-5

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg ￥6000
In-stock
10 mg ￥9300
In-stock
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100 mg   询价  

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Emapalumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1].

体外研究
(In Vitro)

Emapalumab (NI-0501) impairs IFNcR1 and IFNc-Receptor-2 (IFNcR2) interaction induced by IFNc at the cell surface.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Emapalumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 98.86%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Emapalumab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Emapalumab1709815-23-5NI-0501NI0501NI 0501IFNARInterferon-α/β receptorInterferon-alpha/beta receptorhumanized monoclonal antibodyhemophagocytic lymphohistiocytosisIFNc-Receptor-2Inhibitorinhibitorinhibit

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