1. Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Serotonin Transporter
    Endogenous Metabolite
  3. Escitalopram

Escitalopram (Synonyms: (S)-Citalopram; S-(+)-Citalopram)

目录号: HY-14258
产品使用指南

Escitalopram是选择性5-羟色胺重吸收抑制剂(SSRI),Ki为0.89 nM。

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Escitalopram Chemical Structure

Escitalopram Chemical Structure

CAS No. : 128196-01-0

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Escitalopram 的其他形式现货产品:

Other Forms of Escitalopram:

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Description

Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. Target: SSRIs Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.

IC50 & Target

Human Endogenous Metabolite

 

Clinical Trial
Molecular Weight

324.39

Formula

C₂₀H₂₁FN₂O

CAS No.

128196-01-0

SMILES

FC1=CC=C([C@@]2(CCCN(C)C)C(C=CC(C#N)=C3)=C3CO2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Escitalopram(S)-CitalopramS-(+)-CitalopramSerotonin TransporterEndogenous Metabolite5-HTTSERTSLC6A4Inhibitorinhibitorinhibit

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产品名称:
Escitalopram
目录号:
HY-14258
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