2. Gene
  3. CFTR - CF transmembrane conductance regulator Gene

CFTR - CF transmembrane conductance regulator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：CF 跨膜电导调节器

种属: Macaca fascicularis

同用名: ABCC7

基因 ID: 102130331 | 基因类型: protein coding

关于 CFTR

Primary_assembly 3: 144,829,416-145,008,448 forward strand.Macaca_fascicularis_6.0:CM021941.1

This gene has 4 transcripts (splice variants), 215 orthologues and 12 paralogues.

CFTR 基因产物(2)

mRNA Protein Name
XM_045388516.1 XP_045244451.1 cystic fibrosis transmembrane conductance regulator isoform X2
XM_005550598.3 XP_005550655.1 cystic fibrosis transmembrane conductance regulator isoform X1

CFTR 蛋白结构

CFTR_protein

CFTR_protein: cl36858 (0 - 1480)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1481 a.a.
蛋白主名 其他名称

cystic fibrosis transmembrane conductance regulator

ATP-binding cassette sub-family C member 7

Channel conductance-controlling ATPase

cAMP-dependent chloride channel

cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

相关产品

Approval
生物活性分子 (10)
目录号 产品名 作用方式
纯度 是否罕见病
HY-13017 Ivacaftor Agonist 99.90% 是
HY-15206 Glibenclamide Inhibitor 99.92% 是
HY-13262 Lumacaftor Modulator 99.85% 是
HY-15448 Tezacaftor Modulator 99.94% 是
HY-14832 Ataluren Inhibitor 99.82% 是
HY-111772 Elexacaftor Modulator 99.50% 是
HY-B1125 Glucosamine ≥98.0% 是
HY-13017S Ivacaftor-d9 Activator 99.83% 否
HY-13017A Ivacaftor benzenesulfonate Agonist / 否
HY-13017B Ivacaftor hydrate Agonist / 否
Clinical Phase
生物活性分子 (10)
目录号 产品名 作用方式
纯度 Phase
HY-106203A Crinecerfont hydrochloride Antagonist 98.06% Phase 3
HY-15448S Tezacaftor-d4 Modulator ≥97.0% Phase 3
HY-106203 Crinecerfont Antagonist / Phase 3
HY-145603 Vanzacaftor Modulator 98.06% Phase 2
HY-18337 IOWH-032 Inhibitor 99.63% Phase 2
HY-111680 Nesolicaftor Modulator 99.37% Phase 2
HY-126394 Bamocaftor 99.09% Phase 2
HY-109152 Navocaftor Modulator 99.05% Phase 2
HY-109187A Posenacaftor sodium Modulator 99.79% Phase 2
HY-125381 CFTR corrector 2 Modulator 98.29% Phase 2
Pre-clinical Phase
生物活性分子 (58)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16671 CFTR(inh)-172 Inhibitor 99.25% 否
HY-18336 GlyH-101 Inhibitor 98.24% 否
HY-150090 SRI-41315 Activator 99.94% 否
HY-19778 (R)-BPO-27 Inhibitor 99.66% 否
HY-111099 GLPG1837 Agonist 99.86% 否
HY-109027 Cavosonstat Modulator 99.22% 是
HY-N6818 5,​7,​4'-​Trimethoxyflavone Activator 99.65% 否
HY-115878 NJH-2-057 Modulator 98.87% 否
HY-111111 Galicaftor Modulator 98.93% 是
HY-19778A BPO-27 racemate Inhibitor 98.61% 否
HY-150089 SRI-37240 Modulator 99.21% 否
HY-109177 Icenticaftor Activator 99.87% 否
HY-14179 PPQ-102 Inhibitor 99.82% 否
HY-112267 Olacaftor Modulator 99.26% 否
HY-108575 Chromanol 293B Inhibitor ≥99.0% 否
HY-19970 KM11060 Activator 99.59% 否
HY-119936 GLPG2451 Activator 99.68% 否
HY-145603A (R)-Vanzacaftor Modulator 98.07% 否
HY-143344 NJH-2-056 Modulator 98.23% 否
HY-13017S3 Ivacaftor-d4 Agonist ≥96.0% 否
HY-P1108A Astressin 2B TFA Antagonist / 否
HY-15206S1 Glyburide-d3 Inhibitor ≥98.0% 否
HY-P1106A K41498 TFA Antagonist 98.64% 否
HY-103369 PG01 Activator ≥98.0% 否
HY-135279 CFTR corrector 4 Modulator 99.60% 否
HY-13017S2 Ivacaftor-d18 92.92% 否
HY-147249 CFTR corrector 8 Modulator 96.00% 否
HY-N5101 Kobusin Activator 99.93% 否
HY-136939 CFTR corrector 6 Activator 99.87% 否
HY-158002 IDOR-4 Modulator / 否
HY-111772A (R)-Elexacaftor Modulator 99.70% 否
HY-119179 UCCF-853 Modulator 99.93% 否
HY-133013 GLPG-3221 / 否
HY-109187 Posenacaftor Modulator / 否
HY-145126 CP-628006 Activator / 否
HY-15206S Glyburide-d11 Inhibitor / 否
HY-148806 Zatonacaftor Modulator / 否
HY-161753 CFTR potentiator 1 Activator / 否
HY-15206A Glibenclamide potassium Inhibitor / 否
HY-156522 CRF1 receptor antagonist-1 Antagonist / 否
HY-155742 CFTR corrector 12 Modulator / 否
HY-114725 VRT-532 Modulator 98.98% 否
HY-153133 CFTR corrector 11 Modulator / 否
HY-117187 Corr4A Modulator / 否
HY-147315 CFTR corrector 9 Modulator 98.84% 否
HY-13017S1 Ivacaftor-d19 Agonist / 否
HY-P1108 Astressin 2B Antagonist / 否
HY-P3597 Urocortin III (mouse) (free acid) Agonist / 否
HY-164037 Riselcaftor Modulator / 否
HY-112267A (R)-Olacaftor Modulator 98.07% 否
HY-15448A (Rac)-Tezacaftor Modulator / 否
HY-126394B Bamocaftor potassium Modulator / 否
HY-112363 Aloisine A Activator / 否
HY-158144 GLPG2737 Modulator / 否
HY-152264 CFTR activator 1 Activator / 否
HY-158991 I1421 Agonist / 否
HY-109187B (R)-Posenacaftor sodium Inhibitor 98.96% 否
HY-12129 CP 154526 hydrochloride Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens CFTR NCBI NCBI:1080
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