2. Gene
  3. ROCK1 - Rho associated coiled-coil containing protein kinase 1 Gene

ROCK1 - Rho associated coiled-coil containing protein kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 Rho 相关卷曲螺旋蛋白激酶 1

种属: Macaca fascicularis

基因 ID: 102140851 | 基因类型: protein coding

关于 ROCK1

Primary_assembly 18: 60,549,133-60,708,018 forward strand.Macaca_fascicularis_6.0:CM021956.1

This gene has 2 transcripts (splice variants), 212 orthologues and 5 paralogues.

ROCK1 基因产物(3)

mRNA Protein Name
XM_005587068.3 XP_005587125.1 rho-associated protein kinase 1 isoform X2
XM_045377988.1 XP_045233923.1 rho-associated protein kinase 1 isoform X3
XM_005587067.2 XP_005587124.1 rho-associated protein kinase 1 isoform X1

ROCK1 蛋白结构

STKc_ROCK1

STKc_ROCK1: cd05622 (1 - 405)

SbcC

SbcC: COG0419 (421 - 963)

HR1_ROCK1

HR1_ROCK1: cd11639 (488 - 553)

ROCK_SBD

ROCK_SBD: cd22250 (835 - 912)

Rho_Binding

Rho_Binding: pfam08912 (948 - 1013)

ROCK_SBD

ROCK_SBD: cl40587 (1001 - 1057)

PH_ROCK

PH_ROCK: cd01242 (1118 - 1224)

C1_ROCK1

C1_ROCK1: cd20874 (1221 - 1289)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1354 a.a.
蛋白主名 其他名称

rho-associated protein kinase 1

相关产品

Approval
生物活性分子 (12)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10071 Y-27632 Inhibitor 99.97% 否
HY-10583 Y-27632 dihydrochloride Inhibitor 99.98% 否
HY-10341 Fasudil Hydrochloride Inhibitor 99.96% 是
HY-15307 Belumosudil Inhibitor 99.77% 是
HY-15685 Ripasudil Inhibitor 99.92% 否
HY-13911 Hydroxyfasudil Inhibitor 98.42% 否
HY-15307A Belumosudil mesylate Inhibitor 99.89% 是
HY-13911A Hydroxyfasudil hydrochloride Inhibitor 98.88% 否
HY-10341A Fasudil Inhibitor / 否
HY-10341C Fasudil dihydrochloride Inhibitor / 否
HY-10341B Fasudil hydrochloride semihydrate Inhibitor / 否
HY-15685A Ripasudil free base Inhibitor / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-109191 Sovesudil Inhibitor 98.31% Phase 3
HY-109191A Sovesudil hydrochloride Inhibitor 99.79% Phase 3
HY-15687A SAR407899 Inhibitor 99.60% Phase 2
HY-15687 SAR407899 hydrochloride Inhibitor 98.66% Phase 2
HY-16071 AT13148 Inhibitor 99.21% Phase 1
Pre-clinical Phase
生物活性分子 (27)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15392 Chroman 1 Inhibitor 99.38% 否
HY-15556 GSK269962A Inhibitor 99.83% 否
HY-11000 GSK429286A Inhibitor 98.15% 否
HY-119937 ROCK inhibitor-2 Inhibitor 99.87% 否
HY-18990 GSK180736A Inhibitor 98.01% 否
HY-15755 RKI-1447 Inhibitor 98.29% 否
HY-13300 SR-3677 Inhibitor 99.90% 否
HY-12437 BDP5290 Inhibitor 98.80% 否
HY-14362 GSK-25 Inhibitor 99.68% 否
HY-108518 SB-772077B dihydrochloride Inhibitor ≥99.0% 否
HY-100270 Rho-Kinase-IN-1 Inhibitor 99.91% 否
HY-16758 Verosudil Inhibitor 99.18% 否
HY-10319 BAY-549 Inhibitor 99.46% 否
HY-126275 HSD1590 Inhibitor 99.54% 否
HY-110339 RKI-1447 dihydrochloride Inhibitor 98.04% 否
HY-15392A Chroman 1 dihydrochloride Inhibitor 99.11% 否
HY-149266 THK01 Inhibitor 99.80% 否
HY-14227 LIMK-IN-1 Inhibitor 99.33% 否
HY-107209 RKI-1313 Inhibitor ≥98.0% 否
HY-132302 Hu7691 Inhibitor / 否
HY-132302A Hu7691 free base Inhibitor / 否
HY-162596 NRL-1049 Inhibitor / 否
HY-16758A Verosudil hydrochloride Inhibitor / 否
HY-13300A SR-3677 dihydrochloride Inhibitor / 否
HY-15556A GSK269962A hydrochloride Inhibitor / 否
HY-122011 PF-4950834 Inhibitor / 否
HY-125221 DJ4 Inhibitor 98.48% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ROCK1 NCBI NCBI:6093
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