1. Anti-infection
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. Bacterial
    STAT
  3. Golotimod hydrochloride

Golotimod hydrochloride (Synonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride)

目录号: HY-14743B
产品使用指南

Golotimod hydrochloride (SCV 07 hydrochloride) 一种具有抗菌活性的免疫调节肽,可显着提高抗结核治疗的功效,刺激胸腺和脾细胞增殖,并改善巨噬细胞功能。Golotimod hydrochloride (SCV 07 hydrochloride) 抑制 STAT3 信号传导并调节接受放疗或放疗与顺铂联合用药的动物模型中口腔粘膜炎的持续时间和严重程度。Golotimod hydrochloride (SCV 07 hydrochloride) 是复发性生殖器单纯疱疹病毒 2 型 (HSV-2) 的潜在治疗药物。

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Golotimod hydrochloride Chemical Structure

Golotimod hydrochloride Chemical Structure

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥3850 In-stock
5 mg ¥3500 In-stock
10 mg ¥5500 In-stock
50 mg ¥16500 In-stock
100 mg ¥22500 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Other Forms of Golotimod hydrochloride:

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Description

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)[1][2][3].

IC50 & Target

STAT3

 

Molecular Weight

369.80

Formula

C₁₆H₂₀ClN₃O₅

SMILES

O=C(CC[C@@](N)(C(O)=O)[H])NC([H])(C(O)=O)CC1=CNC2=C1C=CC=C2.Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (338.02 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7042 mL 13.5208 mL 27.0416 mL
5 mM 0.5408 mL 2.7042 mL 5.4083 mL
10 mM 0.2704 mL 1.3521 mL 2.7042 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Golotimod hydrochloride
目录号:
HY-14743B
需求量: