2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC6-IN-30

HDAC6-IN-30 (compound 8g) 是一种选择性HDAC6抑制剂，其 IC50 21 nM，可提高细胞蛋白乙酰化水平。

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HDAC6-IN-30

HDAC6-IN-30 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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HDAC6-IN-30 相关抗体

Top Publications Citing Use of Products

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HDAC6-IN-30 (compound 8g) is a selective HDAC6 inhibitor with the IC50 21 nM, and increase cell protein acetylation levels[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa GI50
80 μM
Compound: 8g
Antiproliferative activity against human HeLa cells assessed as growth inhibition incubated for 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition incubated for 72 hrs by MTS assay
[PMID: 38142511]
MDA-MB-231 GI50
87 μM
Compound: 8g
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by MTS assay
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by MTS assay
[PMID: 38142511]
NCI-H1975 GI50
13 μM
Compound: 8g
Antiproliferative activity against human NCI-H1975 cells assessed as growth inhibition incubated for 96 hrs by MTS assay
Antiproliferative activity against human NCI-H1975 cells assessed as growth inhibition incubated for 96 hrs by MTS assay
[PMID: 38142511]
分子量

360.41

Formula

C22H20N2O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HDAC6-IN-30 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC6-IN-30HDACHistone deacetylasesEpigeneticsHistone deacetylase 6Lung cancerSmall moleculeInhibitorinhibitorinhibit

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产品名称：
HDAC6-IN-30
目录号：
HY-157436
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