2. GPCR/G Protein
  3. P2Y Receptor
  4. NF546 hydrate

NF546 hydrate 

目录号: HY-108661A 纯度: ≥97.0%
COA 产品使用指南

摩尔计算器

NF546 (hydrate) 是一种选择性非核苷酸 P2Y11 激动剂，pEC50 为 6.27。NF546 (hydrate) 刺激人单核细胞来源的树突状细胞释放白细胞介素-8。

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NF546 hydrate Chemical Structure

NF546 hydrate Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥900
In-stock
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10 mg   询价  

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Other Forms of NF546 hydrate:

NF546 hydrate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NF546 (hydrate) is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 (hydrate) stimulates release of interleukin-8 from human monocyte-derived dendritic cells[1].

IC50 & Target

pEC50: 6.27 (P2Y11)[1]
体外研究
(In Vitro)

NF546 (hydrate) is relatively selective for P2Y11 over P2Y1, P2Y2, P2Y4, P2Y6, P2Y12, P2X1, P2X2, and P2X2-X3. NF546 (hydrate) (100 μM; 24 hours) is equi-efficacious in stimulating TSP-1 release and inhibiting the LPS-induced release of IL-12p70 in human monocyte-derived dendritic cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

NF546 hydrate 相关抗体:
分子量

1424.01

Formula

C47H44N6Na4O17P4.13.5H2O
性状

固体

颜色

White to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

NF546 hydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF546NF 546NF-546P2Y Receptorselectivenon-nucleotideinterleukinsstimulatesthrombospondin-1secretionLPSInhibitorinhibitorinhibit

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NF546 hydrate
目录号：
HY-108661A
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