1. Immunology/Inflammation Anti-infection
  2. COX Bacterial
  3. Oxyphenbutazone-d9

Oxyphenbutazone-d9  (Synonyms: 羟布宗 d9)

目录号: HY-B1355AS
产品使用指南

Oxyphenbutazone-d9Oxyphenbutazone (HY-B1355A) 的氘代物。Oxyphenbutazone 是一种苯丁酮衍生物,具有抗炎作用。Oxyphenbutazone 是一种非选择性的 COX 抑制剂。Oxyphenbutazone 是保泰松 (Phenylbutazone; HY-B0230) 的代谢物。Oxyphenbutazone 能选择性地杀死不复制的结核分枝杆菌 (Mycobaterium tuberculosis)。

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Oxyphenbutazone-d<sub>9</sub> Chemical Structure

Oxyphenbutazone-d9 Chemical Structure

CAS No. : 1189693-23-9

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  • 生物活性

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  • 参考文献

生物活性

Oxyphenbutazone-d9 is the deuterium labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2][3].

IC50 & Target

COX, Bacteria[2][3]

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

333.43

Formula

C19H11D9N2O3

CAS 号
中文名称

羟布宗 d9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Oxyphenbutazone-d9 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-B1355AS
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