2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. P-gp inhibitor 2

P-gp inhibitor 2 是一种有效的 P-gp 抑制剂。P-gp Inhibitor 2 在过表达 P-gp 的人结肠直肠癌细胞 (SW600 Ad300) 中显示出阿霉素耐药的逆转作用(IC50=0.22 µM)。

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P-gp inhibitor 2 Chemical Structure

P-gp inhibitor 2 Chemical Structure

CAS No. : 2408406-89-1

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P-gp inhibitor 2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].

体外研究
(In Vitro)

P-gp inhibitor 2 (compound 2) exhibits no cytotoxicity (IC50>30 µM) toward human carcinoma (SW600) cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

P-gp inhibitor 2 相关抗体:
分子量

498.53

Formula

C29H26N2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

P-gp inhibitor 2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P-gp inhibitor 22408406-89-1P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243pharmacophoreMarine-Derived fungalSW600 Ad300 cellschrysosporazinedoxorubicincytotoxicityInhibitorinhibitorinhibit

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