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  2. Mitophagy
  3. P62-mediated mitophagy inducer

P62-mediated mitophagy inducer (Synonyms: PMI)

目录号: HY-115576 纯度: >99.0%
产品使用指南

P62-mediated mitophagy inducer 是一种线粒体自噬调节剂,能激活线粒体噬但不招募 Parkin 或者使膜电位崩溃,且在缺乏完整功能的 PINK1/Parkin 通路的细胞中保留活性。

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P62-mediated mitophagy inducer Chemical Structure

P62-mediated mitophagy inducer Chemical Structure

CAS No. : 1809031-84-2

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥1898 In-stock
1 mg ¥1400 In-stock
5 mg ¥2200 In-stock
10 mg ¥4200 In-stock
25 mg ¥9100 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing ΔΨm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway[1].

IC50 & Target

mitophagy[1]

Molecular Weight

392.15

Formula

C₁₄H₉IN₄O₂

CAS No.

1809031-84-2

SMILES

O=[N+](C1=CC(C2=CN(C3=CC=CC(I)=C3)N=N2)=CC=C1)[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 1 mg/mL (2.55 mM; ultrasonic and adjust pH to 3 with 0.1 M HCL)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5500 mL 12.7502 mL 25.5004 mL
5 mM --- --- ---
10 mM --- --- ---
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。 -80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

References

Purity: >99.0%

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× = ×
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Keywords:

P62-mediated mitophagy inducerPMIMitophagyMitochondrial AutophagyInhibitorinhibitorinhibit

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产品名称:
P62-mediated mitophagy inducer
目录号:
HY-115576
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