1. Anti-infection Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Bacterial Antibiotic PDI
  3. Ribostamycin

Ribostamycin  (Synonyms: Vistamycin; SF-733)

目录号: HY-142127
产品使用指南

Ribostamycin (Vistamycin) 是一种广谱氨基糖苷类抗生素 (antibiotic)。Ribostamycin 对革兰氏阴性和革兰氏阳性细菌感染有效。Ribostamycin 还抑制 PDI 的伴侣活性。

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Ribostamycin Chemical Structure

Ribostamycin Chemical Structure

CAS No. : 25546-65-0

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI[1][2].

IC50 & Target

Aminoglycoside

 

体外研究
(In Vitro)

Ribostamycin 抑制 Borrelia burgdorferi 活性,MIC90 为 32 mg/L[2]
Ribostamycin (1-100 μM, 0-15 min) 可抑制 PDI 的分子伴侣活性[3]
Ribostamycin 抑制大肠杆菌 (Escherichia coli) 活性,MIC 为 0.9-7.2 μM[4]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[4]

Cell Line: Escherichia coli strains
Concentration: 0-64 μg/mL
Incubation Time: 14 h
Result: Inhibited Escherichia coli strains with a MIC of 0.9-7.2 μM.
体内研究
(In Vivo)

Ribostamycin (40 mg/kg,肌肉注射,每天,持续 14 天) 对大鼠几乎没有肾毒性 (通过尿液分析评估)[5]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

454.47

Formula

C17H34N4O10

CAS 号
结构分类
初始来源

Streptomyces ribosidificus

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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