2. Cell Cycle/DNA Damage Protein Tyrosine Kinase/RTK JAK/STAT Signaling Vitamin D Related/Nuclear Receptor
  3. Topoisomerase VEGFR c-Met/HGFR EGFR Estrogen Receptor/ERR
  4. Anticancer agent 276

Anticancer agent 276 (Compound 5) 是一种多靶点抗癌剂。Anticancer agent 276 对人类肿瘤细胞具有强效抗癌活性，对 HEPG2 和 MCF7 细胞的 IC50 分别为 6.90 μM 和 4.48 μM。Anticancer agent 276 与多个靶点 (包括拓扑异构酶 II、VEGFR2、c-Met、EGFR 和 ERα) 表现出强效且稳定的相互作用。

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Anticancer agent 276

Anticancer agent 276 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Anticancer agent 276 相关抗体

Top Publications Citing Use of Products

查看 Topoisomerase 亚型特异性产品:

查看所有亚型
Topoisomerase Topo I Topo II

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 276 (Compound 5) is a multi-target anticancer agent. Anticancer agent 276 has a potent anticancer activity against human tumor cells with IC50s of 6.90 and 4.48 μM for HEPG2 and MCF7 cells, respectively. Anticancer agent 276 shows strong and stable interactions across multiple targets, including Topoisomerase II, VEGFR2, c-Met, EGFR and ERα[1].

IC50 & Target[1]

Topoisomerase II

 

ERα

 

VEGFR2

 

分子量

395.46

Formula

C24H21N5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 276 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 276Anticancer agent276Anticancer agent-276TopoisomeraseVEGFRc-Met/HGFREGFREstrogen Receptor/ERRVascular endothelial growth factor receptorEpidermal growth factor receptorErbB-1HER1Multi-targetAnticancerTopoisomerase IIVEGFR2c-MetERαHEPG2 cellsMCF7 cellsInhibitorinhibitorinhibit

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