2. Peptides
  3. BIM-23027

BIM-23027 是一种 sst2 受体的选择性激动剂 (EC50=0.32 nM)，与生长抑素 (SRIF, 一种环状十四肽) 具有相似的作用。BIM-23027 刺激多巴胺释放，并由 Glu 依赖机制介导。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

BIM-23027 Chemical Structure

BIM-23027 Chemical Structure

CAS No. : 78981-49-4

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

BIM-23027 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic tetradecapeptide. BIM-23027 stimulates dopamine release, which is mediated by a Glu-dependent mechanism[1][2].

IC50 & Target

EC50: 0.32 nM (sst2)[2]
体外研究
(In Vitro)

BIM-23027 (10,50 和 100 nM; 90分钟) 显著增加多巴胺水平[1]。
BIM-23027 (50 nM; 100 nM SRIF 处理前 15 分钟孵育) 显著减弱了天然肽的作用[1]。
BIM-23027 (30 nM; 30 分钟) 卡威酚刺激的基底鳞状细胞增加 60-70%，EC50 为 0.29 nM[2]。
BIM-23027 与大鼠结肠粘膜 [125I]Tyr11-SRIF 结合位点的亚群相互作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BIM-23027 相关抗体:
分子量

794.94

Formula

C43H54N8O7
CAS 号
Sequence Shortening

Cyclo[{(NMe)Ala}-FWKTF]
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIM-2302778981-49-4BIM23027BIM 23027OthersInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
BIM-23027
目录号：
HY-P3958
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z