2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. CGP 12177 hydrochloride

CGP 12177 hydrochloride  (Synonyms: (±)-CGP 12177 hydrochloride)

目录号: HY-101393A 纯度: 99.57%
COA 产品使用指南

摩尔计算器

CGP 12177 ((±)-CGP 12177) hydrochloride 是一种 β Adrenergic Receptor 配体。 CGP 12177 hydrochloride 是 β1- 和 β2-AR 的高亲和力拮抗剂。 CGP 12177 hydrochloride 还显示出以较低的亲和力与 β3-AR 相互作用，并对啮齿动物和人类 β3-AR 表现出部分激动剂活性。 CGP 12177 hydrochloride 对大鼠肺动脉中的 α1-AR 表现出部分激动剂特性。

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CGP 12177 hydrochloride Chemical Structure

CGP 12177 hydrochloride Chemical Structure

CAS No. : 64208-32-8

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规格 价格 是否有货 数量
5 mg ￥1434
In-stock
10 mg ￥2290
3 - 4 周
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CGP 12177 hydrochloride 相关抗体

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery[1].

IC50 & Target

Beta-1 adrenergic receptor

 

Beta-2 adrenergic receptor

 

Beta-3 adrenergic receptor

 

α1-adrenergic receptor

 

分子量

315.80

Formula

C14H22ClN3O3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

CGP 12177 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CGP 1217764208-32-8(±)-CGP 12177CGP12177CGP-12177Adrenergic ReceptorBeta ReceptorIntrapulmonary ArteryInhibitorinhibitorinhibit

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产品名称：
CGP 12177 hydrochloride
目录号：
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