2. Cell Cycle/DNA Damage PROTAC Apoptosis
  3. DNA/RNA Synthesis PROTACs Apoptosis
  4. FPP29

FPP29 是一种新型、高效、安全的全肽基 FOXM1 PROTAC 降解剂。FPP29 显著抑制细胞划痕愈合，诱导凋亡 (apoptosis)，抑制克隆形成。FPP29 具有细胞毒性 (IC50 = 3.65 μM)。FPP29 可以用于癌症如肝癌的研究。(CPP: HY-P0133, VHL 配体: HY-P11493, 连接子: HY-W013664, FOXM1 配体: HY-P11494)

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

FPP29

FPP29 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

FPP29 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

查看所有亚型
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FPP29 is a novel, efficient, and safe peptide based FOXM1 PROTAC degrader. FPP29 significantly inhibits cell scratch healing, induces apoptosis, and suppresses clone formation. FPP29 has cytotoxicity (IC50 = 3.65 μM). FPP29 can be used for research on cancers such as liver cancer. (CPP: HY-P0133, VHL Ligand: HY-P11493, Linker: HY-W013664, FOXM1 Ligand: HY-P11494)[1]

IC50 & Target[1]

VHL

 

分子量

3267.72

Formula

C145H228N56O32
Sequence

Ala-Trp-Trp-Asn-Thr-Glu-Trp-Gly-Ser-Ala-Leu-Ala-Pro-Tyr-Ile-Pro-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg
Sequence Shortening

AWWNTEWGSALAPYIPRRRRRRRRR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FPP29 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FPP29FPP 29FPP-29DNA/RNA SynthesisPROTACsApoptosisFOXM1PROTACapoptosiscancerInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
FPP29
目录号：
HY-P11228
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z